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Selected publications; 2006 - 2008

Platination of full length tRNA(Ala) and truncated versions of the acceptor stem and anticodon loop
Papsai P, Snygg AS, Aldag J, Elmroth, SKC
DALTON TRANSACTIONS, 38, 5225-5234,  2008

Cisplatin and siRNA interference with structure and function of Wnt-5a mRNA: design and in vitro evaluation of targeting AU-rich elements in the 3 ' UTR
Hagerlof M, Papsai P, Hedman HK,  Jungwirth U, Jenei V, Elmroth SKC
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY,13(3),  385-399, 2008

{1-[1-(3-Carboxypropanamido)ethyl]-1',2-bis(diphenylphosphino)ferrocene-kappaP-2,P'}dichloridoplatinum(II) dichloromethane 1.25-solvate
Spencer LC, Bjelosevic H, Darkwa J, Elmroth SKC, Persson T
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE,64,M164-U1562,Part 1, 2008

Construction of polyamine-modified uridine and adenosine derivatives - evaluation of DNA binding capacity and cytotoxicity in vitro
Ghatnekar J, Hagerlof M, Oredsson S, Alm K, Elmroth SKC, Persson T
BIOORGANIC & MEDICINAL CHEMISTRY,15(23),7426-7433, 2007

The polyamines spermidine and spermine retard the platination rate of single-stranded DNA oligomers and plasmid
Snygg AS, Hung M, Elmroth SKC
JOURNAL OF INORGANIC BIOCHEMISTRY, 101(8),1153-1164, 2007

Platination of the siRNA sense-strand modulates both efficacy and selectivity in vitro
Hagerlof M, Hedman H, Elmroth SKC
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 361(1),14-19,2007 

More pronounced salt dependence and higher reactivity for platination of the hairpin r(CGCGUUGUUCGCG) compared with d(CGCGTTGTTCGCG)
Hagerlof M, Papsai P, Chow CS, Elmroth SKC
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY,11(8),974-990, 2006

Kinetic preference for interaction of cisplatin with the G-C-rich wobble basepair region in both tRNA(Ala) and Mh(Ala)
Papsai P, Aldag J, Persson T, Elmroth SKC
DALTON TRANSACTIONS,29,3515-3517,2006 

{mu-2-[1-(N,N-Dimethylamino)ethyl]ferrocene-1,1'-diylbis(diphenylphosphine)-kappa P-2 : P '}bis[thiocyanatogold(I)]
Sam ZA, Elmroth SCK, Roodt A, Muller AJ
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 62,M1699-M1701, Part 7, 2006

Synthesis and structural characterisation of novel platinum-based drug candidates with extended functionality by incorporation of bis(diphenylphosphino)ferrocene units as metal chelators
Bjelosevic H, Spegel C, Snygg AS, Gorton L, Elmroth SKC, Persson T
TETRAHEDRON, 62(18),4519-4527, 2006