MPS seminar Harm Kampinga

Friday June 8, at 15:15, Kemicentrum sal B
Professor Harm H. Kampinga, Department of Cell Biology, Section of Radiation and Stress Cell Biology, University Medical Center, University of Groningen, the Netherlands
Chaperones, protein quality control and protein misfolding diseases
The proper function and regulation of heat shock proteins is crucial for cell survival. Increasing failure of cellular repair and quality control mechanisms is involved in many age-related syndromes, including cancer, neurodegenerative diseases, and atrial fibrillation. In a recent paper, Prof. Kampinga’s and coworkers describe the discovery that during cell division, irreversibly damaged, stored proteins are asymmetrically distributed and inherited by only one daughter cell in an evolutionary conserved mechanism preventing transmission of damaged proteins to the longest lived daughter cell (Rujano et al 2006 PLoS Biology 4, 2325-35).

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