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Research at CMPS

The focus of the research activities at CMPS is within some major areas of modern biochemistry, structural biology and biophysical chemistry. Our research interests cover topics such as membrane protein structure and function; structure, function and dynamics of enzymes; molecular interactions and large macromolecular assemblies; bio-electrochemistry; RNA, DNA and viruses.

A wide range of biochemical and biophysical methods are used in CMPS. Among those are NMR, X-ray crystallography, LC-MALDI-TOF/TOF and state-of-the art ESI mass spectrometry (Orbitrap Velos Pro), microcalorimetry (ITC, DSC), surface plasmon resonance (Biacore 3000), ellipsometry, chromatography, DNA sequencing, and protein engineering, CD spectroscopy and dynamic light scattering (DLS). 

List of supervisors for research projects:

Ingemar André- protein design, protein evolution, computer modelling of proteins, directed evolution

Tommy Cedervall- nanoparticles, nanosafety, protein analyses

Urban Johanson - aquaporins and other membrane proteins, transient receptor potential (TRP) ion channels

Derek Logan - protein crystallography, cryo-EM, ribonucleotide reductase enzymes

Martin Lundqvist- amyloid peptides, protein interactions with nanoparticles, nanoparticle characterization

Sara Snogerup Linse - amyloid proteins and peptides, calcium-binding proteins

Herwig Schüler -  enzymology, development of cancer drugs and antibiotics

Henrik Stålbrand - carbohydrate degrading enzymes, enzyme engineering for green chemistry

Susanna Horsefield- aquaporins, mitochondrial pyruvate carrier, structural biology, protein-protein interactions

Mikael Akke - protein dynamics, structure, function; thermodynamics protein-ligand binding; NMR spectroscopy

Kristofer Modig - NMR spectroscopy

Pär Söderhjelm - theoretical chemistry and computer modelling

Kristine Steen Jensen-