Research at CMPS
The focus of the research activities at CMPS is within some major areas of modern biochemistry, structural biology and biophysical chemistry. Our research interests cover topics such as membrane protein structure and function; structure, function and dynamics of enzymes; molecular interactions and large macromolecular assemblies; bio-electrochemistry; RNA, DNA and viruses.
A wide range of biochemical and biophysical methods are used in CMPS. Among those are NMR, X-ray crystallography, LC-MALDI-TOF/TOF and state-of-the art ESI mass spectrometry (Orbitrap Velos Pro), microcalorimetry (ITC, DSC), surface plasmon resonance (Biacore 3000), ellipsometry, chromatography, DNA sequencing, and protein engineering, CD spectroscopy and dynamic light scattering (DLS).
List of supervisors for research projects:
Ingemar André- protein design, protein evolution, computer modelling of proteins, directed evolution
Tommy Cedervall- nanoparticles, nanosafety, protein analyses
Urban Johanson - aquaporins and other membrane proteins, transient receptor potential (TRP) ion channels
Derek Logan - protein crystallography, cryo-EM, ribonucleotide reductase enzymes
Martin Lundqvist- amyloid peptides, protein interactions with nanoparticles, nanoparticle characterization
Sara Snogerup Linse - amyloid proteins and peptides, calcium-binding proteins
Herwig Schüler - enzymology, development of cancer drugs and antibiotics
Henrik Stålbrand - carbohydrate degrading enzymes, enzyme engineering for green chemistry
Susanna Horsefield- aquaporins, mitochondrial pyruvate carrier, structural biology, protein-protein interactions
Mikael Akke - protein dynamics, structure, function; thermodynamics protein-ligand binding; NMR spectroscopy
Kristofer Modig - NMR spectroscopy
Pär Söderhjelm - theoretical chemistry and computer modelling